Azoles are nitrogen, sulfur, and oxygen-containing compounds with a five-membered ring system that comprises thiadiazole, oxadiazole, triazole, imidazole, isoxazole, pyrazole, and other rings. Mainly known as antifungal agents, azole derivatives demonstrate many other biological properties including antidiabetic, immunosuppressant, antiinflammatory, and anticancer activities. Azoles also exhibit α-glucosidase inhibition, which include derivatives of thiadiazoles, oxadiazoles, triazoles, diamine-bridged coumarinyl oxadiazole conjugates with phenylenediamine, benzidine and 4,4′-oxydianiline linkers, and 5,6-diaryl-1,2,4-triazine thiazoles.

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