Azoles - Fluconazole - (Digital) Tree Post Series - Continuation to "Cytochromes - Cytochomes P450 - ERG11 gene - Non-Elaborate Posts - Post 5 (Continuation to Post 4)" - Post 9

 
In Candida albicans, ERG11 mutations are one of the primary mechanisms of fluconazole resistance. This makes C. albicans a model species for studying the molecular biology of azole resistancr.

Non-albicans Candida species, such as C. glabrata and C. tropicalis, also develop ERG11 mutations. However, the specific mutations and their impacts vary, reflecting species-specific enzyme differences.


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